HORDB

ID: hor004642
Uniprot ID: Q3ECD6(23-74)
Protein name: CLAVATA3/ESR (CLE)-related protein 1
Gene name: CLE1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Family: CLV3/ESR signal peptide family
Source: Plant
Expression: [CLE1p]: Mostly expressed in roots and seedlings, and, to a lower extent, in stems and apex.
Disease: NA
Comments: NA
Taxonomy: Arabidopsis (genus), Camelineae (tribe), Brassicaceae (family), Brassicales (order), malvids, rosids, Pentapetalae, Gunneridae, eudicotyledons, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
GO MF: GO:0033612 receptor serine/threonine kinase binding
GO BP: GO:0030154 cell differentiation; GO:0045168 cell-cell signaling involved in cell fate commitment
GO CC: GO:0005576 extracellular region; GO:0048046 apoplast

Sequence: SRPMFPNADGIKRGRMMIEAEEVLKASMEKLMERGFNESMRLSPGGPDPRHH
Length: 52(23-74)
Propeptide: MANLKFLLCLFLICVSLSRSSASRPMFPNADGIKRGRMMIEAEEVLKASMEKLMERGFNESMRLSPGGPDPRHH
Signal peptide: MANLKFLLCLFLICVSLSRSSA
Modification: T44 Hydroxyproline;T47 Hydroxyproline
Glycosylation: T37 N-linked (GlcNAc...) asparagine;T47 O-linked (Ara...) hydroxyproline
Mutagenesis: 41-41R->K,N: No impact on proteolysis.

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004642_AF2.pdb

hor004642_ESM.pdb

Mass:	683568	Formula:	C251H409N79O75S6
Absent amino acids:	CQTWY	Common amino acids:	EMRGP
pI:	9.44	Basic residues:	11
Polar residues:	11	Hydrophobic residues:	11
Hydrophobicity:	-89.04	Boman Index:	-14184
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	48.85
Instability Index:	4235.58	Extinction Coefficient cystines:	0
Absorbance 280nm:	0